Contact

Prof. Dr. T. Leinders-Zufall

Center for Integrative Physiology and Molecular Medicine (CIPMM)

Saarland University, School of Medicine

Department of Physiology

Kirrbergerstrasse 100, Bldg 48

D-66424 Homburg

Germany

Latest news:

April 2026: Frank Zufall is appointed guest professor at the Walther Straub Institute of Pharmacology and Toxicology at the Ludwig Maximilians Universität (LMU) in Munich.

(email: f.zufall @lmu.de)

Ideal efficiacy photoswitching for chromocontrol of TRPC4/5 channel functions in live tissue. Müller M, Niemeyer K, Ojha NK, Porav SA, Vinayagam D, Urban N, Büchau F, Oleinikov K, Makke M, Bauer CC, Johnson AV, Muench SP, Zufall F, Bruns D, Schwarz Y, Raunser S, Leinders-Zufall T, Bon RS, Schaefer M, Thorn-Seshold O (2026) Nature Chemical Biology.

Tuft cell IL-17RB restrains IL-25 bioavailability and reveals context-dependent ILC2 hypoproliferation. Feng X, Andersson T, Flüchter P, Gschwend J, Berest I, Muff JL, Lechner A, Gondrand A, Westermann P, Brander N, Carchidi D, DeTenorio JC, Pan T, Boehm U, Klose CSN, Artis D, Messner CB, Leinders-Zufall T, Zufall F, Schneider C (2025) Nature Immunology.

TRPC5 controls the adrenaline-mediated counter regulation of hypoglycemia. Bröker-Lai J, Terol JR, Richter C, Mathar I, Wirth, A, Kopf S, Moreno-Perez A, Büttner M, Tan LL, Makke M, Poschet G, Hermann J,, Tsvilovskyy V, Haberkorn U, Wartenberg P, Susperreguy S, Berlin M, Ottenheijm R, Phiippart K, Wu M, Wiedermann T, Herzig S, Belkacemi A, Terral RL, Agarwal N, Camacho Londono JE, Klebl B, Dinkel K, Zufall F, Nussbaumer P, Boehm U, Hell R, Nawroth P, Birnbaumer L, Leinders-Zufall T, Kuner R, Zorn M, Bruns D, Schwarz Y, Freichel M (2024) EMBO J, 43(23):5813-5836

Widespread distribution of luteinizing hormone/ choriogonadotropin receptor in human juvenile angiofibroma: Implicaations for a sex-specific nasal tumor. Wemmert, Pyrski, Pillong, Linxweiler, Zufall, Leinders-Zufall T, Schick B (2024) Cells 13, 1217

Congratulations to Dr. Kohei Koike for his outstanding doctoral thesis and receiving the Dr.-Eduard-Martin Preis !

News Saarland University Award

Congratulations to Dr. Brett Boonen for best short oral presentation at Behring-Röntgen and Leopoldina Tuft Cell Symposium in Gießen !

Optical activation of photoswitchable TRPC ligands in the mammalian olfactory system using laser scanning confocal microscopy. Ojha NK, Zufall F, Leinders-Zufall T (2023) In: Goldstein, B.J., Matsunami, H. (eds) The Olfactory System. Methods in Molecular Biology, vol 2710. Humana, New York, NY.

A succinate/SUCNR1-brush cell defense program in the tracheal epithelium. Perniss A, Boonen B, Tonach S, Thiel M, Poharkar K, Anouri WM, Keshavarz M, Papadakis T, Wiegand S, Pfeil U, Richter K, Althaus M, Obewinkler J, Schütz B, Boehm U, Offermans S, Leinders-Zufall T, Zufall F, Kummer W (2023) Science Advances.